Direct access to benzo[b]furans through palladium-catalyzed oxidative annulation of phenols and unactivated internal alkynes
Direct access to benzo[b]furans through palladium-catalyzed oxidative annulation of phenols and unactivated internal alkynes
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Date
2013-04-22
Authors
Kuram, Malleswara Rao
Bhanuchandra, M.
Sahoo, Akhila K.
Journal Title
Journal ISSN
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Abstract
2,3-Disubstituted benzo[b]furans are prepared in one step from commercially available phenols and readily accessible unactivated internal alkynes (see scheme). This Pd-catalyzed oxidative annulation has a broad substrate scope and allows access to a wide range of benzo[b]furans. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Description
Keywords
alkynes,
benzo[b]furans,
oxidative annulation,
phenols,
regioselectivity
Citation
Angewandte Chemie - International Edition. v.52(17)