Highly functionalised (γ-azido/γ-fluoro-β-iodo/)vinyl derivatives from phosphorus based allenes or allenoates: I⋯O halogen bonding interactions

dc.contributor.author Anitha, Mandala
dc.contributor.author Kumara Swamy, K. C.
dc.date.accessioned 2022-03-27T09:47:34Z
dc.date.available 2022-03-27T09:47:34Z
dc.date.issued 2019-01-01
dc.description.abstract Multifunctional γ-azido/γ-fluoro-β-iodo-vinyl phosphine oxides/phosphonates/esters/sulfone were synthesised by iodination followed by azidation/fluorination of phosphorus-based allenes or allenoates (allenyl esters) or a sulphur based allene. Surprisingly, the reaction of (γ,β)-diiodo-vinyl-phosphonate with TBAF [n-Bu4NF] led to the corresponding allenylphosphonate; in contrast, the use of CsF in a similar reaction led to novel γ-diiodo-allenylphosphonate along with the corresponding non-halogenated allenylphosphonate. The combination AgF2/CuBr could be used to obtain the γ-fluoro-β-iodo-vinyl phosphine oxides and related phosphorus-free γ-fluoro-β-iodo-vinyl esters. In many cases, I⋯O halogen to oxygen non-covalent bonding interactions ('halogen bonding') involving the phosphoryl (PO) oxygen, as evidenced by single crystal X-ray crystallography, are also observed.
dc.identifier.citation Organic and Biomolecular Chemistry. v.17(23)
dc.identifier.issn 14770520
dc.identifier.uri 10.1039/c9ob00715f
dc.identifier.uri http://xlink.rsc.org/?DOI=C9OB00715F
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/13310
dc.title Highly functionalised (γ-azido/γ-fluoro-β-iodo/)vinyl derivatives from phosphorus based allenes or allenoates: I⋯O halogen bonding interactions
dc.type Journal. Article
dspace.entity.type
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