Copper-catalyzed aerobic oxidative coupling of aminocarbazoles and aminoindoles: Synthesis of diindolophenazines and dipyrrolophenazines

Abstract

We have developed a simple method for the synthesis of diindolophenazine and dipyrrolophenazine derivatives by the aerobic oxidative coupling of 3-aminocarbazole and 2,3-dimethyl-5-aminoindole derivatives, respectively, in the presence of catalytic CuBr (10 mol%) in DMSO at 80 °C while open to air. © Georg Thieme Verlag Stuttgart New York.