Enantiomerically pure piperazines via NaBH < inf > 4 < /inf > /I < inf > 2 < /inf > reduction of cyclic amides

dc.contributor.author Harish, Vagala
dc.contributor.author Periasamy, Mariappan
dc.date.accessioned 2022-03-27T09:06:39Z
dc.date.available 2022-03-27T09:06:39Z
dc.date.issued 2017-01-01
dc.description.abstract Enantiomerically pure (3S,7R,8aS)-3-phenyloctahydropyrrolo[1,2-a]pyrazine-7-ol, (3S,7R,8aS)-3-methyl octahydropyrrolo[1,2-a]pyrazine-7-ol, (3S,7R,8aS)-3-isopropyloctahydropyrrolo[1,2-a]pyrazine-7-ol and (3S,7R,8aS)-3-isobutyloctahydropyrrolo[1,2-a]pyrazine-7-ol 16d were synthesized via preparation of the corresponding cyclic amides from enantiomerically pure L-proline and hydroxyproline derivatives followed by reduction using sodium borohydride-iodine.
dc.identifier.citation Tetrahedron Asymmetry. v.28(1)
dc.identifier.issn 09574166
dc.identifier.uri 10.1016/j.tetasy.2016.12.002
dc.identifier.uri https://www.sciencedirect.com/science/article/abs/pii/S0957416616303652
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/12431
dc.title Enantiomerically pure piperazines via NaBH < inf > 4 < /inf > /I < inf > 2 < /inf > reduction of cyclic amides
dc.type Journal. Article
dspace.entity.type
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