Highly Regioselective Synthesis of Oxindolyl-Pyrroles and Quinolines via a One-Pot, Sequential Meyer-Schuster Rearrangement, Anti-Michael Addition/C < inf > (sp < sup > 3 < /sup > ) < /inf > -H Functionalization, and Azacyclization
Highly Regioselective Synthesis of Oxindolyl-Pyrroles and Quinolines via a One-Pot, Sequential Meyer-Schuster Rearrangement, Anti-Michael Addition/C < inf > (sp < sup > 3 < /sup > ) < /inf > -H Functionalization, and Azacyclization
| dc.contributor.author | Yaragorla, Srinivasarao | |
| dc.contributor.author | Dada, Ravikrishna | |
| dc.contributor.author | Rajesh, P. | |
| dc.contributor.author | Sharma, Manju | |
| dc.date.accessioned | 2022-03-27T08:36:28Z | |
| dc.date.available | 2022-03-27T08:36:28Z | |
| dc.date.issued | 2018-03-31 | |
| dc.description.abstract | A one-pot, sequential Meyer-Schuster (MS) rearrangement of oxindole-derived propargyl alcohols to the corresponding α,β-unsaturated enones and their anti-Michael addition, followed by intramolecular azacyclization is described in a highly regioselective manner using Ca(OTf)2 as the promoter. Further, we described the one-pot MS rearrangement, followed by C(sp3)-H functionalization of 2-methyl azaarenes at α-carbon of these doubly activated alkenes. Control experiments and computational calculations were performed to propose the reaction mechanism. | |
| dc.identifier.citation | ACS Omega. v.3(3) | |
| dc.identifier.uri | 10.1021/acsomega.8b00147 | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acsomega.8b00147 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/11176 | |
| dc.title | Highly Regioselective Synthesis of Oxindolyl-Pyrroles and Quinolines via a One-Pot, Sequential Meyer-Schuster Rearrangement, Anti-Michael Addition/C < inf > (sp < sup > 3 < /sup > ) < /inf > -H Functionalization, and Azacyclization | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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