Production of a novel indole ester from 2-aminobenzoate by Rhodobacter sphaeroides OU5

dc.contributor.author Sunayana, M. R.
dc.contributor.author Sasikala, Ch
dc.contributor.author Ramana, Ch V.
dc.date.accessioned 2022-03-27T03:46:10Z
dc.date.available 2022-03-27T03:46:10Z
dc.date.issued 2005-02-01
dc.description.abstract Culture supernatants of Rhodobacter sphaeroides OU5 grown in the presence of 2-aminobenzoate gave an orange-red color-reaction with Salper's reagent, suggesting the presence of an indole derivative. This production was light-dependent and inducible only with 2-aminobenzoate. Replacement of 2-aminobenzoate with other 2-substituted benzoates did not result in the formation of indole. Fumarate appeared to be the conjugating molecule with 2-aminobenzoate, resulting in the formation of an indole derivative. The purified indole derivative was orange-brown in color, with a yields 0.34 mM from 1 mM 2-aminobenzoate. Infrared analysis suggested an indole ester and 1H NMR analysis indicated an indole carboxylate, esterified with a terpenoid alcohol. The indole ester has a mass of 441 with the molecular formula C27H39NO4. The IUPAC name of the compound is (3 E,5 E)-14-hydroxy-3,7,11-trimethyl-3,5-tetradecadienyl 2-(hydroxymethyl)-1 H-indole-3-carboxylate; and the common name given to this compound is sphestrin. © Society for Industrial Microbiology 2005.
dc.identifier.citation Journal of Industrial Microbiology and Biotechnology. v.32(2)
dc.identifier.issn 13675435
dc.identifier.uri 10.1007/s10295-004-0193-y
dc.identifier.uri https://academic.oup.com/jimb/article/32/2/41-45/5992726
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/5335
dc.subject 2-aminobenzoate
dc.subject Aromatic hydrocarbons
dc.subject Indole-ester
dc.subject Photobiotransformation
dc.subject Rhodobacter sphaeroides OU5
dc.title Production of a novel indole ester from 2-aminobenzoate by Rhodobacter sphaeroides OU5
dc.type Journal. Article
dspace.entity.type
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