[3 + 2]-Cycloaddition of nonstabilized azomethine ylides. 10. An efficient strategy for the construction of x-azatricyclo[m.n.0.0 < sup > a,b < /sup > ]alkanes by intramolecular cycloaddition of cyclic azomethine ylide

Abstract

(equation presented) Various new structural entities related to x-azatricyclo[m.n.0.0a,b]alkanes are constructed by the intramolecular [3 + 2] dipolar cycloaddition of nonstabilized cyclic azomethine ylides. The ylide is generated by the sequential double desilylation of N-alkyl α,α′-bis(trimethylsilyl)cyclic amines using Ag(I)F as a one-electron oxidant.