A new route to the synthesis of ellipticine quinone from isatin
A new route to the synthesis of ellipticine quinone from isatin
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Date
2014-01-29
Authors
Ramkumar, Nagarajan
Nagarajan, Rajagopal
Journal Title
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Abstract
1-(2-Oxo-2-(pyridin-4-yl)ethyl)indoline-2,3-dione can be prepared and converted by treatment with sodium hydroxide into 2-isonicotinoyl-1H-indole-3- carboxylic acid as a key intermediate which can be transformed into ellipticine quinone in a two step sequence. © 2013 Elsevier Ltd. All rights reserved.
Description
Keywords
Alkaloids,
Ellipticine quinone,
o-Lithiation,
Rearrangement,
Total synthesis
Citation
Tetrahedron Letters. v.55(5)