A facile method for the synthesis of various 3-substituted indoles via Michael addition reaction using NbCl < inf > 5 < /inf >
A facile method for the synthesis of various 3-substituted indoles via Michael addition reaction using NbCl < inf > 5 < /inf >
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Date
2015-02-01
Authors
Yaragorla, Srinivasarao
Kumar, G. Srikanth
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Abstract
A mild and efficient method for the synthesis of various 3-substituted indoles is described via a Michael addition reaction using NbCl5 as a Lewis acid catalyst. Simple reaction conditions, short reaction times, less amount of catalyst loading, high yields and substrate diversity are the advantages of this methodology.
Description
Keywords
3-Substituted indoles,
Chalcones,
Heterocyclic compounds,
Michael addition,
Natural products,
NbCl5
Citation
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry. v.54B(2)