Concise total synthesis of cytotoxic natural products (+) and (-)-muricatacin
Concise total synthesis of cytotoxic natural products (+) and (-)-muricatacin
No Thumbnail Available
Date
2010-08-01
Authors
Yaragorla, Srinivasarao
Muthyala, Ramaiah
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
A short and efficient total synthesis of antitumor natural products (+) and (-)-muricatacin is described in four steps with an overall yield of 47%. The key reactions involved in the synthesis are Ph3P mediated isomerization and asymmetric dihydroxylation. © ARKAT USA, Inc.
Description
Keywords
Butyrolactone,
Dihydroxylation,
Muricatacin,
Natural product,
Total synthesis,
Triphenylphosphine mediated isomerization
Citation
Arkivoc. v.2010(10)