Ketones as electrophiles in two component Baylis-Hillman reaction: A facile one-pot synthesis of substituted indolizines
Ketones as electrophiles in two component Baylis-Hillman reaction: A facile one-pot synthesis of substituted indolizines
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Date
2014-03-14
Authors
Basavaiah, Deevi
Veeraraghavaiah, Gorre
Badsara, Satpal Singh
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Abstract
2-Alkanoyl(aroyl)-pyridines have been successfully used for coupling with alkyl vinyl ketones under the influence of TMSOTf providing a facile protocol for the synthesis of substituted indolizines, thus demonstrating the application of ketones as electrophiles in a two component Baylis-Hillman reaction. © The Royal Society of Chemistry 2014.
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Organic and Biomolecular Chemistry. v.12(10)