Synthesis of cis-2-aryl-3-pyrrolidine carboxylic esters via diastereoselective cyclization of γ-imino esters using a TiCl < inf > 4 < /inf > /Et < inf > 3 < /inf > N reagent system
Synthesis of cis-2-aryl-3-pyrrolidine carboxylic esters via diastereoselective cyclization of γ-imino esters using a TiCl < inf > 4 < /inf > /Et < inf > 3 < /inf > N reagent system
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Date
2004-08-09
Authors
Suresh, Surisetti
Periasamy, Mariappan
Journal Title
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Abstract
Facile synthesis of cis-2-aryl-3-pyrrolidine carboxylates from readily accessible γ-imino esters by intramolecular cyclization mediated by a TiCl4/Et3N reagent system is described. © 2004 Elsevier Ltd.
Description
Keywords
Imino esters,
Intramolecular cyclization,
Pyrrolidines
Citation
Tetrahedron Letters. v.45(33)