Convenient synthetic methods to C < inf > 2 < /inf > symmetric 3,4-diphenylpyrrolidines
Convenient synthetic methods to C < inf > 2 < /inf > symmetric 3,4-diphenylpyrrolidines
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Date
2000-01-01
Authors
Rao, Vutukuri Dharma
Periasamy, Mariappan
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Abstract
Convenient methods of synthesis of racemic and optically pure 3,4- diphenylpyrrolidine derivatives, involving oxidative coupling of ethyl phenylacetate using TiCl4/Et3N and reduction of the dl-2,3-diphenylsuccinic acid or the corresponding cyclic imide with NaBH4/I2 reagent in crucial steps, are described.
Description
Keywords
3,4- diphenylpyrrolidine,
Amines,
Chiral dicarboxylic acid,
Cyclic imide,
Diol,
Oxidative coupling,
Reductions
Citation
Synthesis