The synthesis of neosporol: A trichothecene in search of a natural product
The synthesis of neosporol: A trichothecene in search of a natural product
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Date
1988-01-01
Authors
Ziegler, Frederick E.
Nangia, Ashwini
Schulte, Gayle
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Abstract
The synthesis of neosporol 14, a yet to be discovered trichothecene, is described. The critical reaction is a highly diastereoselective Claisen rearrangement that sets the C5C6 stereochemistry. © 1988.
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Tetrahedron Letters. v.29(14)