Construction of 2-Thiabicyclo[3.3.1]nonanes by Organocatalytic Asymmetric Formal [3+3] Cycloaddition
Construction of 2-Thiabicyclo[3.3.1]nonanes by Organocatalytic Asymmetric Formal [3+3] Cycloaddition
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Date
2018-04-30
Authors
Ramachary, Dhevalapally B.
Reddy, P. Srinivasa
Gujral, Jagjeet
Journal Title
Journal ISSN
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Abstract
Powerful asymmetric desymmetrization of thiane-3,5-diones through formal [3+3] cycloaddition with alkyl vinyl ketones has been disclosed to access functionally rich 2-thiabicyclo[3.3.1]nonanes in very good yields with excellent enantio- and diastereoselectivities by using organocatalysis.
Description
Keywords
Alkyl vinyl ketones,
Annulation,
Asymmetric synthesis,
Bicyclo[3.3.1]nonanes,
Organocatalysis
Citation
European Journal of Organic Chemistry. v.2018(16)