Synthesis of methyl-(3-oxo-2h-[1,4]-benzoxa /thiazin-6-yl)-pyrazole-5-carboxylates & isoxazole-3-carboxylates as possible cox-2 / 5-lox inhibitors
Synthesis of methyl-(3-oxo-2h-[1,4]-benzoxa /thiazin-6-yl)-pyrazole-5-carboxylates & isoxazole-3-carboxylates as possible cox-2 / 5-lox inhibitors
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Date
2008-01-01
Authors
Reddy, G. Jagath
Rao, K. Srinivasa
Jayaveera, K. N.
Sailaja, S.
Reddanna, P.
Reddy, D. Bharat
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Abstract
A series of Methyl-(3-oxo-2H-[1,4]benzoxa/thiazin-6-yl)pyrazole-5-carboxylates (5 & 6) and isoxazole-3-carboxylates (7 & 8) have been synthesized and tested for their COX-2 / 5-LOX inhibitory activities. © 2008, by Walter de Gruyter GmbH & Co. All rights reserved.
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Heterocyclic Communications. v.14(1-2)