New, convenient methods of synthesis and resolution of 1,2-amino alcohols

dc.contributor.author	Periasamy, Mariappan
dc.contributor.author	Sivakumar, Sangarappan
dc.contributor.author	Reddy, Meda Narsi
dc.date.accessioned	2022-03-27T09:09:26Z
dc.date.available	2022-03-27T09:09:26Z
dc.date.issued	2003-01-01
dc.description.abstract	Oximes of α-keto esters are reduced to obtain the corresponding amino alcohols using NaBH4 in combination with I2, CH 3COOH, TiCl4, ZrCl4, COCl2, H 2SO4, and TMS-Cl in 60-85% yields. The racemic phenylglycinol, phenylalaninol, and 2-aminobutanol are resolved using dibenzoyl-L-tartaric acid to obtain enantiomeric samples of > 98% ee.
dc.identifier.citation	Synthesis
dc.identifier.issn	00397881
dc.identifier.uri	10.1055/s-2003-41046
dc.identifier.uri	http://www.thieme-connect.de/DOI/DOI?10.1055/s-2003-41046
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/12506
dc.subject	Amino alcohols
dc.subject	Boron
dc.subject	Enantiomeric resolution
dc.subject	Esters
dc.subject	Oximes
dc.title	New, convenient methods of synthesis and resolution of 1,2-amino alcohols
dc.type	Journal. Article
dspace.entity.type

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