A novel curcumin-artemisinin coamorphous solid: Physical properties and pharmacokinetic profile
A novel curcumin-artemisinin coamorphous solid: Physical properties and pharmacokinetic profile
| dc.contributor.author | Suresh, Kuthuru | |
| dc.contributor.author | Chaitanya Mannava, M. K.C. | |
| dc.contributor.author | Nangia, Ashwini | |
| dc.date.accessioned | 2022-03-27T09:25:30Z | |
| dc.date.available | 2022-03-27T09:25:30Z | |
| dc.date.issued | 2014-01-01 | |
| dc.description.abstract | Here we report a curcumin-artemisinin coamorphous solid (1:1) prepared by rotavaporization and a dramatic increase in the pharmacokinetic profile of curcumin (AUC0-12 2.6 μg h mL-1, Cmax 1 μg mL-1) administered as CUR-ART to SD rats. PXRD and FESEM analysis explains the molecular basis for the solubility enhancement of coamorphous CUR-ART. | |
| dc.identifier.citation | RSC Advances. v.4(102) | |
| dc.identifier.uri | 10.1039/c4ra11935e | |
| dc.identifier.uri | http://xlink.rsc.org/?DOI=C4RA11935E | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12887 | |
| dc.title | A novel curcumin-artemisinin coamorphous solid: Physical properties and pharmacokinetic profile | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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