A study toward understanding the role of a phosphorus stereogenic center in (5S)-1,3-diaza-2-phospha-2-oxo-3-phenylbicyclo(3.3.0)octane derivatives as catalysts in the borane-mediated asymmetric reduction of prochiral ketones
A study toward understanding the role of a phosphorus stereogenic center in (5S)-1,3-diaza-2-phospha-2-oxo-3-phenylbicyclo(3.3.0)octane derivatives as catalysts in the borane-mediated asymmetric reduction of prochiral ketones
No Thumbnail Available
Date
2005-12-12
Authors
Basavaiah, Deevi
Chandrashekar, Vanampally
Das, Utpal
Reddy, Gone Jayapal
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Representative diastereomeric pairs of chiral catalysts, containing the (5S)-1,3-diaza-2-phospha-2-oxo-3-phenylbicyclo(3.3.0)octane moiety, with different stereochemistry at the phosphorus stereogenic center, have been synthesized and their stereoselection in the borane-mediated asymmetric reduction of representative prochiral ketones has been described. © 2005 Elsevier Ltd. All rights reserved.
Description
Keywords
Citation
Tetrahedron Asymmetry. v.16(24)