New methods of resolution and purification of racemic and diastereomeric amino alcohol derivatives using boric acid and chiral 1,1′-bi-2-naphthol
New methods of resolution and purification of racemic and diastereomeric amino alcohol derivatives using boric acid and chiral 1,1′-bi-2-naphthol
| dc.contributor.author | Periasamy, M. | |
| dc.contributor.author | Kumar, N. S. | |
| dc.contributor.author | Sivakumar, S. | |
| dc.contributor.author | Rao, V. D. | |
| dc.contributor.author | Ramanathan, C. R. | |
| dc.contributor.author | Venkatraman, L. | |
| dc.date.accessioned | 2022-03-27T09:09:44Z | |
| dc.date.available | 2022-03-27T09:09:44Z | |
| dc.date.issued | 2001-06-01 | |
| dc.description.abstract | Resolution of the racemic amino alcohol derivatives 1-6 is readily achieved to obtain enantiomerically enriched compounds using chiral 1,1′-bi-2-naphthol and boric acid in solvents such as CH3-CN, THF, and MeOH. Purification of the diastereomeric mixture 7 has also been carried out following this method. The corresponding intermediate ammonium borate complexes were also characterized by X-ray diffraction methods. | |
| dc.identifier.citation | Journal of Organic Chemistry. v.66(11) | |
| dc.identifier.issn | 00223263 | |
| dc.identifier.uri | 10.1021/jo0057755 | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/jo0057755 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12514 | |
| dc.title | New methods of resolution and purification of racemic and diastereomeric amino alcohol derivatives using boric acid and chiral 1,1′-bi-2-naphthol | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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