New potent cytotoxic lamellarin alkaloids from Indian ascidian Didemnum obscurum
New potent cytotoxic lamellarin alkaloids from Indian ascidian Didemnum obscurum
| dc.contributor.author | Reddy, S. Malla | |
| dc.contributor.author | Srinivasulu, M. | |
| dc.contributor.author | Satyanarayana, N. | |
| dc.contributor.author | Kondapi, Anand K. | |
| dc.contributor.author | Venkateswarlu, Y. | |
| dc.date.accessioned | 2022-03-27T05:16:18Z | |
| dc.date.available | 2022-03-27T05:16:18Z | |
| dc.date.issued | 2005-09-26 | |
| dc.description.abstract | Chemical investigations of the ascidian Didemnum obscurum has resulted in the isolation of four new lamellarin alkaloids, lamellarin-ζ (1), lamellarin-η (2), lamellarin-φ (3) and lamellarin-χ (4) along with seven known lamellarins, lamellarin-K (5), lamellarin-I (6), lamellarin-J (7), lamellarin-K triacetate (8), lamellarin-L triacetate (9), lamellarin-F (10) and lamellarin-T diacetate (11). The structures of the compounds 1-11 were established by detailed analysis of NMR spectral data. Cytotoxic activity of the isolates has been done against coloractal cancer cells. © 2005 Elsevier Ltd. All rights reserved. | |
| dc.identifier.citation | Tetrahedron. v.61(39) | |
| dc.identifier.issn | 00404020 | |
| dc.identifier.uri | 10.1016/j.tet.2005.07.067 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0040402005012755 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/7593 | |
| dc.subject | Ascidians | |
| dc.subject | Coloractal cancer cells | |
| dc.subject | Cytotoxic activity | |
| dc.subject | Lamellarin alkaloids | |
| dc.title | New potent cytotoxic lamellarin alkaloids from Indian ascidian Didemnum obscurum | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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